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XB-IMG-169881

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Figure 7. Models for CPLANE function and structure(a) Schematic of normal IFT. Peripheral proteins are assembled onto the IFT-A core in the cytoplasm and injected together with IFT-B for bi-direction transport in axonemes. (b) In the absence of CPLANE, IFT-A core particles lacking peripheral proteins are injected into axonemes and traffic normally; IFT-B enters axonemes but fails to move in a retrograde direction and accumulates.

Image published in: Toriyama M et al. (2016)

Image downloaded from an Open Access article in PubMed Central. Image reproduced on Xenbase with permission of the publisher and the copyright holder.

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