Xenbase Image ID: 170568

Figure 4. znf703 is a true target of Pax3 and Zic1. (a and b) Fold induction of snai2 (a) and znf703 (b) by expression of pax3GR and zic1GR in animal cap explants (microarray data; Bae et al., 2014). (c and d) Injection in one blastomere at the two-cell stage of MOs blocking Pax3 (pax3MO; 40 ng) Zic1 (zic1MO; 40 ng) function resulted in a strong reduction of snai2 expression (c),r while only the most anterior expression domain of znf703 was affected (d) at the neurula stage. The injected side is to the right as indicated by the presence of the lineage tracer (Red-Gal). The percentage of affected embryos is indicated in the upper right corner. Dorsal views, anterior to top. Image published in: Hong CS and Saint-Jeannet JP (2017) Copyright © 2017. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue snai2.L slug, snai2-a, snai2-b, Snail2, xSlu, xslug, XSnail2 X. laevis Throughout NF stage 15 neural plate border cranial neural crest znf703.L znf703-a, znf703-b X. laevis Sometime during NF stage 18 to NF stage 25 chordal neural plate hindbrain Image source: Published Larger Image Printer Friendly View

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