Xenbase Image ID: 170597

Figure 4. Establishment of directional ASE asymmetry in C. elegans. Priming and boosting of lsy-6 miRNA throughout the ASEL cell lineage leads to the ASEL identity. At the 4-cell stage, activated Notch receptor in the ASER precursor inhibits priming and boosting events of lsy-6 miRNA, leading to the ASER identity. TF, transcription factor; purple, active ASER-promoting molecules; blue, active ASEL-promoting molecules; grey, less active or inactive molecules; circles represent cells. Image published in: Alqadah A et al. (2018) Copyright © 2018. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

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