Xenbase Image ID: 170721

Figure 3. Protocadherin-15 is located at the calyceal processes of photoreceptor cells in X. tropicalis larvae. (A) In 4 dpf larvae, protocadherin-15 (green) is located around the base of the lectin-labeled (white) rod (R) and cone (C) outer segments (OS). Protocadherin-15 colocalizes with F-actin (red) that fill the calyceal processes (CPs). (B) In pre-embedding immunogold electron micrographs, silver-enhanced immunogold particles showed protocadherin-15 to be localized at the CPs surrounding the rod (top) and cone (bottom) OS. Sparse gold particles also decorate the lamellar membrane in cones (asterisks). (C) Protocadherin-15 immunolabeled gold particles (arrowheads) were localized with filaments connecting the CPs to the OS plasma membrane in rods (top) and cones (bottom). Bars: (A) 10 µm; (A, SEM image) 5 µm; (B) 200 nm; (C) 100 nm. Image published in: Schietroma C et al. (2017) © 2017 Schietroma et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license Gene Synonyms Species Stage(s) Tissue pcdh15 cdhr15, dfnb23, LOC108695740, LOC108697174, ush1f X. tropicalis Sometime during NF stage 45 to NF stage 47 photoreceptor layer retinal rod cell retinal cone cell Image source: Published Larger Image Printer Friendly View

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