XB-IMG-171177
Xenbase Image ID: 171177
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Supplementary Figure 6
(A) Knock-down of PGAM5 by siRNA transfection strongly enhanced responsiveness of murine C2C12 cells to
WNT3A stimulation as determined by TOP-Flash reporter gene assays normalized to β-Galactosidase. (B) PGAM5
knock-down in HEK293T cells resulted in stabilization of cytoplasmic β-Catenin and upregulation of the feedback
target AXIN2. Image published in: Rauschenberger V et al. (2017) Copyright © 2017. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |