Xenbase Image ID: 171538

Supplementary Figure 2 CPLANE interactors. (a) Venn diagram showing overlap between the interactomes of Intu, Fuz, and Wdpcp. The intersection of the three (“combined CPLANE interactome”) contains ~250 proteins. (b) Additional components of the extended CPLANE protein network built using data from tandem affinity purification of Intu, Fuz, Wdpcp, IFT-A, and the published NPHP network and thresholded for most likely network members. (c) The CPLANE proteins associate with IFT-A proteins and poorly characterized cilia-related proteins (arrows indicates baitprey in Fuz, Wdpcp and Intu pulldowns). (d) The core CPLANE complex was identified by reciprocal pulldowns. (e) Co-IP with in vitro translated proteins confirms CPLANE interactions with Jbts17 (a fragment of Jbts17 was used, as the very large size of this protein made in vitro translation intractable). Image published in: Toriyama M et al. (2016) Image downloaded from an Open Access article in PubMed Central. Image reproduced on Xenbase with permission of the publisher and the copyright holder. Larger Image Printer Friendly View

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