Xenbase Image ID: 171540

Supplementary Figure 4 Effect of a Joubert-associated CPLANE allele. (a) Jbts17 truncated mutants and fragments construct used in this study. (b) Fluorescence images in multi-ciliated cells expressing GFP-tagged Jbts17 wild-type, R1569*, R2406* and amino acids 1770-2318. (c,d) Fluorescence images GFP-tagged Inturned (c) and GFP-Ift43 (d) in multi-ciliated cells in control, Jbts17 knockdown, Jbst17-wild-type or truncated mutant (R1569*) expressing cells in Jbts17 knockdown embryos. The graph shows the normalized fluorescence intensity of GFP-Inturned (c) and GFP-IFT43 (d) at basal bodies, as described in legend to Supplementary Figure 2. Scale bars, 10 m. Image published in: Toriyama M et al. (2016) Image downloaded from an Open Access article in PubMed Central. Image reproduced on Xenbase with permission of the publisher and the copyright holder. Gene Synonyms Species Stage(s) Tissue cplane1.L c5orf42, jbts17 X. laevis Sometime during NF stage 18 to NF stage 29 and 30 cilium basal body multiciliated cell Image source: Published Larger Image Printer Friendly View

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