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Fig. 2. Adgra2 protein. a. Schematic overview of X. laevis Adgra2 protein precursor (NP_001083670.1). Individual domains are highlighted in different colors and amino acid (aa) numbers are given for orientation within the protein. The region of binding of the WMISH probe is highlighted in purple. b. Primary protein sequence of X. laevis Adgra2. Different domains are highlighted as in a. c. Amino acid comparison of Adgra2 sequences between different species. Given are the total numbers of aa as well as the percentage of identity of the overall protein sequences and different domain sequences compared to Homo sapiens ADGRA2. Colors are used similar to a. GPCR: G protein-coupled receptor; GPS: GPCR proteolysis site; HRD: hormone receptor domain; IG: immunoglobulin; LRR: leucine rich repeat; PDZ: PDZ binding domain; SP: signal peptide; 7TMR: seven transmembrane receptor domain. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)

Image published in: Seigfried FA et al. (2018)

Copyright © 2018. Image reproduced with permission of the Publisher, Elsevier B. V.

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