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Figure 10. Transcriptomic changes induced by ERK3 knockdown are similar to those induced by tfap2a knockdown. A, Sample preparation for the second microarray experiment. Control MO (80 ng), ERK3 MO1/2 (40 ng each of MO1 and MO2) or TFAP2A MO1/2 (40 ng each of MO1 and MO2) was injected into animal regions of all blastomeres at the 4-cell stage. B, Venn diagrams for genes downregulated or upregulated >1.5-fold upon ERK3 or tfap2a knockdown. C, D, Scatter plots represent the fold changes of all (C) or cell junction-related (D) gene expression levels in ERK3 or tfap2a morphants relative to those in control morphants. r, correlation coefficient.
Image published in: Takahashi C et al. (2018) Copyright © 2018. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |