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Fig. S3.
Gene set enrichment analysis of differentially expressed genes between LiCl- and UV-treated embryos not captured by the comparative transcriptomics of DMZ and VMZ. (A-C) Analysis of genes differentially expressed between LiCl- and UV-treated embryos, but not captured by the transcriptional comparison of DMZ and VMZ. Heatmap (A) and regression plot (B) of indicated transcriptional comparisons. (B) Pearson coefficient, ρ = 0.34. Student’s two-tailed t-test, p = 1.4e-35. (C) Plots show the number of upregulated genes and associated hypergeometric p-values of enrichment for specific biological processes (BPs) of the Gene Ontology (GO) project. Selected BPs refer to early developmental processes (i), signalling (ii), and differentiation of germ layers and their derivatives (iii). Image published in: Monteiro RS et al. (2018) © 2018 The Authors. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View |