Xenbase Image ID: 172698

Fig. S4. PFKFB4 is required for neural crest migration. (A,D) WISH analysis of neural crest migration at tadpole stages. When Pfkfb4 MO is injected, embryos display decreased Twist expression and neural crest migration defects (B), when compared to control embryos (A). (C) In contrast, the coinjection of Pfkfb4 mRNA with Pfkfb4 MO restores Twist expression and NC migration, showing that the neural crest migration defects are due to PFKFB4 knowckdown. A-C are side views, anterior is to the right. Image published in: Figueiredo AL et al. (2017) Copyright © 2017. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue twist1.L twist, twist1-a, twist1-b, X-twi, Xtwi, Xtwist X. laevis Sometime during NF stage 22 to NF stage 24 cranial neural crest mandibular crest hyoid crest branchial crest migratory neural crest cell Image source: Published Larger Image Printer Friendly View

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