Xenbase Image ID: 172749

Fig. S2. Verification of RA-responsiveness (A) Ectodermal explants from vegt/nog/cyp26a1-injected embryos (in vitro) or whole embryos (in vivo) were treated with RA or left untreated. Analysis of candidate gene expression was by use of the Nanostring technology. (B) RA-signalling was either impaired by Cyp26a1 RNA injection into the two dorsal blastomers at the four-cell stage and dorsal tissue dissected at stage 11 (red dotted line), or whole embryos were treated with BMS453 from stage 9 to 12/14 and analyzed using Nanostring. (C) Venn diagram illustrating the number of genes verified for their RA-inducibility in vitro and in vivo as well as for their RA-dependence in vivo. Image published in: Gere-Becker MB et al. (2018) © 2018. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

Return to previous page