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Fig. S8. Hnf1β is not a sufficient substitute for the induction of pancreatic gene expression by RA (A) Programmed explants were from embryos co-injected with Hnf1β-GR RNA at the two-cell stage. Treatment with dexamethasone (DEX) and RA was at the equivalent of gastrula stage. At the equivalent of stage 28, total RNA was isolated and analyzed by RT-PCR. (B) RT-PCR analysis for pancreatic and endodermal genes as well as for the known direct Hnf1β target Hnf4α.

Image published in: Gere-Becker MB et al. (2018)

© 2018. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license

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