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Fig. S12 Effects of Fzd4/Fzd4s downregulation on the expression of various endodermal organ marker genes Eight-cell stage embryos were injected with RNA coding for β-galactosidase and either Fzd4/ Fzd4s-morpholino or the corresponding mismatch-morpholino. At stage 38/39, embryos were used for WMISH against Pdx1 (pancreas, duodenum), hHex (liver), Nkx2.1 (thyroid, lung) and IFABP (stomach, intestine). Image published in: Gere-Becker MB et al. (2018) © 2018. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue nkx2-1.L nkx2.1, titf1, ttf1, Xnkx-2.1, xnkx2-1 X. laevis Sometime during NF stage 37 and 38 to NF stage 39 thyroid primordium lung bud hhex.L hex, tHex, XHex X. laevis Sometime during NF stage 37 and 38 to NF stage 39 liver fabp2.L fabp2-A, fabp2-a, fabp2-b, IFABP X. laevis Sometime during NF stage 37 and 38 to NF stage 39 alimentary system Image source: Published Larger Image Printer Friendly View

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