Xenbase Image ID: 172859

Supplementary Figure 2: Expression of pronephric markers in wt and ruby mutant embryos. Embryos from a heterozygous carrier cross were fixed at 36-37 stage and the expression of pronephric markers: pax8 (paired box 8), pax2 (paired box 2), atp1a1 (ATPase, Na+/K+ transporting, alpha 1 polypeptide) , slc7a8 (solute carrier family 7 (amino acid transporter light chain, L system), member 8), slc5a9 (solute carrier family 5 (sodium/glucose cotransporter), member 9), smp-30 (senescence marker protein-30), hnf1-b (HNF1 homeobox b) and cdh16 (cadherin 16), were studied by WMISH. Embryos were genotyped to confirm the mutation after imaging. Arrowheads indicate abnormal pronephros. Image published in: del Viso F et al. (2012) Copyright ©2012 del Viso et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue pax8 pax-8, XPax-8, XPax8 X. tropicalis Sometime during NF stage 35 and 36 to NF stage 37 and 38 pronephric nephrostome hindbrain pronephric tubule pronephric duct atp1a1 atp1a1-a, atp1a1-b, K-ATPase, Na+/K+ ATPase, Na+K+ ATPase, Na+K+ATPase X. tropicalis Sometime during NF stage 35 and 36 to NF stage 37 and 38 pronephric duct otic vesicle pronephric tubule head pronephric kidney slc5a9 sglt1k, sglt4, XSGLT1K X. tropicalis Sometime during NF stage 35 and 36 to NF stage 37 and 38 pronephric kidney pronephric tubule hnf1b hnf-1beta, hnf1-beta, hnf1beta, lfb3, tcf2, vhnf1 X. tropicalis Sometime during NF stage 35 and 36 to NF stage 37 and 38 pronephric kidney pronephric tubule pax2 LOC108697493, pax-2, pax2-a, pax2-b, XPax-2, XPax2 X. tropicalis Sometime during NF stage 35 and 36 to NF stage 37 and 38 pronephric nephron pronephric tubule pronephric kidney otic vesicle midbrain-hindbrain boundary hindbrain pronephric nephrostome slc7a8 lat2, lpi-pci, MGC52933, XAA2 X. tropicalis Sometime during NF stage 35 and 36 to NF stage 37 and 38 pronephric kidney rgn regucalcin, smp30, xsmp-30, xsmp30 X. tropicalis Sometime during NF stage 35 and 36 to NF stage 37 and 38 pronephric kidney cdh16 cadherin-16, KSP-cadherin X. tropicalis Sometime during NF stage 35 and 36 to NF stage 37 and 38 pronephric duct pronephric kidney pronephric tubule Image source: Published Larger Image Printer Friendly View

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