Xenbase Image ID: 173206

Figure 7. Dkk2 neural crest-inducing activity requires active Wnt/b-catenin signaling. (a) Unilateral injection of dkk2 plasmid DNA (50 pg) expanded snai2 expression domain laterally (arrowhead). This activity was blocked in the context of b-catenin- (b-catMO; 20 ng), Lrp6- (Lrp6MO; 20 ng) or Wnt8-(Wnt8MO; 40 ng) depleted embryos. The injected side (arrowheads) is to the right as indicated by the presence of the lineage tracer (Red-Gal). Dorsal views, anterior to top. (b) Quantification of the phenotypes. The number of embryos analyzed (n) is indicated on the top of each bar. Image published in: Devotta A et al. (2018) © 2018, Devotta et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue snai2.L slug, snai2-a, snai2-b, Snail2, xSlu, xslug, XSnail2 X. laevis Throughout NF stage 14 neural crest neural plate border Image source: Published Larger Image Printer Friendly View

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