XB-IMG-173207
Xenbase Image ID: 173207
Figure 8. Dkk2 mediates its activity independently of GSK3. (a) BIO treatment (10 mM) expanded sox10 expression domain anteriorly. Unilateral
injection of Dkk2SMO (30 ng) reduced sox10 expression a phenotype that cannot be rescued by BIO treatment. In contrast the Wnt inhibitory activity of
Dkk1 (50 pg) on sox10 expression was efficiently rescued by BIO treatment. The injected side (arrowheads) is to the right as indicated by the presence
of the lineage tracer (Red-Gal). Dorsal views, anterior to top. (b) Quantification of the phenotypes. The number of embryos analyzed (n) is indicated on
the top of each bar.
Image published in: Devotta A et al. (2018) © 2018, Devotta et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license
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