Xenbase Image ID: 173251

Figure 5. The putative model of Xbra-Smad-1-mediated synergistic regulation of ventx1.1 transcriptional activation and neurogenesis inhibition in VMZ during early Xenopus development. The putative synergistic transcriptional activation of ventx1.1 (−180) promoter is regulated by the physical interaction of Smad-1 and Xbra in Xenopus embryos. BMP-4/Smad-1 and FGF/Xbra mediate a crosstalk in VMZ, inhibiting neurogenesis in a Ventx1.1-dependent manner during embryonic development of Xenopus. Image published in: Kumar S et al. (2018) © The Author(s) 2018. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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