XB-IMG-173290
Xenbase Image ID: 173290
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Fig. S2. Alignment of amino acid sequences of Otx2 and Otx5/Crx among
vertebrates.
Abbreviations of species are Xenopus laevis (Xl), Xenopus tropicalis (Xt), Danio rerio
(Dr), Gallus gallus (Gg), Mus musculus (Mm) and Homo sapiens (Hs). Protein
sequences were obtained from the NCBI database: Xl_Otx2.L (NP_001084955),
Xl_Otx5.L (NP_001081916), Xt_Otx2 (NP_001016177), Xt_Otx5 (NP_001016021),
Dr_Otx2 (NP_571326), Dr_Otx5 (NP_851848), Gg_Otx2 (NP_989851), Gg_Otx5
(NP_001288716), Mm_Otx2 (NP_001273412), Mm_Crx (NP_031796), Hs_Otx2
(NP_001257453), Hs_Crx (AAH53672). Boxes coloured in green, homeodomainY
blue, SIWSPAS motifY yellow, repeated Otx tail motifY red, Otx2 mutation sites (P133
and P134) that were reportedly associated with human ocular malformation. Blue or
magenta letters, consensus motifs for Akt and Cdks. Bold cases, putative
phosphorylation sites of Otx2 as shown in this study. Image published in: Satou Y et al. (2018) Copyright © 2018. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |