Xenbase Image ID: 173296

Fig. 1. Dose-dependent effects of celecoxib on Xenopus embryo lethality and malformation. The chemical structure of celecoxib (A), which has a molecular formula of C17H14F3N3O2S and a molecular weight of 381.373 g/mol. Xenopus embryos that were exposed to celecoxib showed concentration-dependent phenotypic malformations, including abnormal gut coiling, truncal oedema and severe haemorrhage (B). As the celecoxib concentration increased, embryo survival rates decreased, while the rate and severity of malformations increased (C). Image published in: Yoon YH et al. (2018) Copyright © 2018. This image is reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

Return to previous page