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Fig. 2. Celecoxib severely affected hepatic, intestinal and cardiac development.Xenopus embryos exposed to 7.5 mg/L celecoxib exhibited more severe gut and cardiac effects, associated with haemorrhage (indicated by arrows) and oedema, than did those exposed to 5 mg/L celecoxib (A). Xenopus embryos at stages 36 and 46 showed celecoxib concentration-dependent downregulation of the expression of heart-, liver- and intestine-specific markers, determined by RT-PCR (B). EF1α served as the internal control.

Image published in: Yoon YH et al. (2018)

Copyright © 2018. This image is reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

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