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Fig 4. Simplified example of spherical stage image similarity clustering. Early development stages are routinely photographed from different directions to maximise information about the expression pattern. Reference and comparison images for the same gene and stage are compared under multiple transformations (scale, rotation, shear) to identify the set of transformations that minimises their dissimilarity. Here we see that a 91.5o rotation and a 1.01 scaling suggest the most likely transformation between these two images. All images from the same gene and stage are compared with each other to identify images from (probably) the same view-point. See also Fig 3B. https://doi.org/10.1371/journal.pcbi.1006077.g004 Image published in: Patrushev I et al. (2018) © 2018 Patrushev et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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