Xenbase Image ID: 173949

Fig. 3. Gene activation by Bix1 and Bix3. Xenopus embryos were injected with RNA (200 pg) encoding Bix1 or Bix3 or were left uninjected. Animal pole regions were dissected at late blastula stage 9 and cultured to the equivalent of early gastrula stage 10.5, when they were assayed for expression of the indicated genes by real-time PCR. Bix3 causes a decrease in expression of the control transcript plakoglobin but activates Sox17α and goosecoid to high levels. It does not induce expression of cerberus or XHex. Bix1 is a powerful inducer of Xhex and also activates expression of cerberus. Inset shows data normalised to levels of plakoglobin expression. Image published in: Trindade M et al. (2003) Copyright © 2003. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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