Xenbase Image ID: 173950

Fig. 7. Rescue of apoptosis by injection of 200 pg Bix3 RNA but not Bix1. (A) Uninjected embryos at stage 19. (B) Embryos injected at the one-cell stage with a Bix3 antisense morpholino oligonucleotide begin to undergo apoptosis. (C) Embryos injected at the one-cell stage with a control morpholino oligonucleotide appear normal. (D-F). Embryos injected at the one-cell stage with Bix3 antisense morpholino oligonucleotide together with the indicated amounts of Bix1 RNA which lacks the 5′ untranslated region against which the oligonucleotide is directed. Rescue is not observed at any concentration of RNA. (G-I) Embryos injected at the one-cell stage with Bix3 antisense morpholino oligonucleotide together with the indicated amounts of Bix3 RNA which lacks the 5′ untranslated region against which the oligonucleotide is directed. Apoptosis is 'rescued' by 200 pg RNA (H) but not by 100 pg (G) or 400 pg (I). Image published in: Trindade M et al. (2003) Copyright © 2003. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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