Xenbase Image ID: 173998

Figure 2: Wdr5 depletion affects cilia morphology in the LRO of Xenopus tropicalis. (a) Cilia in control and wdr5 morphant Xenopus LROs marked by anti-acetylated α-tubulin (green) and F-actin marked by phalloidin (red). (b, c) Number of cilia normalized to the LRO area (b) and length of cilia (c) between uninjected controls and wdr5 morphants. Data is presented as box plot with 95% confidence interval. ‘n’ = number of embryos. (d) Number of cilia posteriorly localized in the LRO cells in uninjected controls and wdr5 morphants. Experiments were repeated 2 times. ★ and ★★★ indicate P < 0.05 and P < 0.0005. Image published in: Kulkarni SS and Khokha MK (2018) Copyright © 2018. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue tuba4b alpha tubulin, alpha-tubulin, tuba4, tuba4a X. tropicalis Sometime during NF stage 16 to NF stage 17 left-right organizer cilium Image source: Published Larger Image Printer Friendly View

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