Xenbase Image ID: 174018

Figure S5. Loss of XREST/NRSF function results in a persistent alteration of the patterning of the central nervous system. Anterior views of Xenopus larvae, showing the expression of Sox2 RNA. A control embryo is shown on the left; three embryos which were injected with 500 pg of dnXREST DNA in one cell at the 2-cell stage, and exposed to dexamethasone at stage 9 are shown to the right. Note the expansion of the Sox2-expressing domain in the side derived from the injected cell (shown to the right) and the loss of the normal contour of the eye field. Image published in: Olguín P et al. (2006) Copyright © 2006. This image is reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue sox2.S anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 X. laevis Throughout NF stage 21 neural crest eye primordium neural fold Image source: Published Larger Image Printer Friendly View

Return to previous page