XB-IMG-174125
Xenbase Image ID: 174125
Figure S6. Effects of Eya1 overexpression on NPB markers and other ectodermal TFs. A-J: Expression of PPE (Eya1, Sox3), NC (FoxD3), neural plate (Sox3) markers and early ectodermal TFs in dorsal views of neural plate stage Xenopus embryos after injection of Eya1 mRNA. Anterior is to the bottom. Control side is shown on the left and injected side on the right (as indicated by blue LacZ staining). Reductions (arrows) and increased or ectopic expression domains (asterisks) in the neural (green) and non-neural ectoderm (orange) compared with the control side (arrowheads) are indicated. Green lines indicate broadening of the neural plate and lateral displacement of NPB markers on the injected side (bright green) versus control side (dark green). Insets show alternative phenotypes. K: Summary of regulatory interactions. Arrows indicate ability of Six1 to promote expression of TFs. Bars indicate ability of Six1 to repress TFs. Faint colors indicate less frequent phenotypes. See Additional file 1: Table S9 for numbers. (PDF 1906 kb) Image published in: Maharana SK and Schlosser G (2018) © Schlosser et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license
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