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Figure 5. Acetaldehyde inhibits the expression of organizer-specific genes. Embryos were treated with EtOH (0.5%) or AcAL (5 µM) alone or together with 4MP (1 mM) to inhibit the ADH activity. (a–f) In situ hybridization analysis of the effects of EtOH and AcAL treatments on gsc expression. (a) control, (b) EtOH, (c) AcAL, (d) 4MP, (e) EtOH + 4MP and (f) AcAL + 4MP treated embryos. (g) qPCR analysis of the effect of the same treatments on chordin expression. n = 3, The values denote mean ± SEM. P values - *p < 0.05; **p < 0.01; ns, not significant.

Image published in: Shabtai Y et al. (2018)

© The Author(s) 2017. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license

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