Xenbase Image ID: 174466

Fig. 1. Siamois and Twin are regulated by β-Catenin. (A) The positioning of two dorsal signaling centers at blastula. The BCNE center expresses Chordin (Chd), Noggin (Nog), Siamois (Sia), Twin (Twn), Xenopus nodal-related 3 (Xnr3), FoxA4a/Pintallavis/HNF3β, Anti-dorsalizing morphogenetic protein (ADMP). D, dorsal; V, ventral. (B) The effect of β-Cat-MO, demonstrating that BCNE center genes require β-Catenin. (C–F) Blocking of Xnr inductive events by CerS mRNA injection inhibits Chordin expression at gastrula but not at blastula (when the BCNE is active), while Siamois and Twin are independent of Xnrs. Ornithine decarboxylase (ODC) was used as loading control. Image published in: Ishibashi H et al. (2008) Copyright © 2008. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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