Xenbase Image ID: 174613

Figure S5. Conserved syntenic regions between mammalian and Xenopus chromosome regions containing Interleukin 6 family cytokines and receptors. (A) Table showing interleukin 6 family members in human genome together with their receptors. Crosses indicate the components of each cytokine receptor complex. * Genes unidentified in Xenopus genome. (B) Interleukin 6 (IL6) gene synteny. (C) Interleukin 11 (IL11) gene synteny. (D) Cardiotrophin 1 gene synteny (CTF1). (E) Ciliary neurotrophic factor (CNTF) and cardiotrophin like cytokine 1 factor (CLCF1) genes synteny. (F) Ciliary neurotrophic factor receptor (CNTFR) and Interleukin 11 receptor alpha (IL11RA) gene synteny. (G) Interleukin 6 receptor (IL6R) gene synteny. Gene names symbol are according to HUGO. The chromosome number for human (HAS), mouse (MMU) and the two subgenomes of Xenopus laevis (XLAL and XLAS) is indicated. For Xenopus ctf1 genes, XLAL and XLAS correspond to scaffold 22 and 87 respectively. Genes are represented as colored boxes with the arrow indicating the orientation of the transcription unit. Boxes with the same color correspond to ortholog genes. The following versions of the genomes used to establish are as follows: Human, GRCH38.p7; mouse, GRCm38; Xenopus laevis, Version 9.1; Xenopus tropicalis, Version 8.0. The drawing is not on scale to avoid complexity. Image published in: Jalvy S et al. (2019) Copyright © 2019. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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