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Figure 6—figure supplement 2. Conditional knockdown of Arid3a during nephric regeneration causes the reduction of cell cycle progression.The upper panel shows the experimental design. arid3a.L-antisense-MO inactivated by arid3a.L-Photo-MO is injected at the one-cell stage, and UV exposure is performed at stage 29, followed by nephrectomy at stages 37/38 and then incubation for 72 hr. The fixed nephrectomized X. laevis were subjected to immunostaining with phosphorylated histone H3. The lower panel shows the statistical analysis. The significance of differences between the UV-untreated and UV-treated embryos was calculated by two-tailed unpaired t-test (p=0.0278). The error bars indicate SEM.

Image published in: Suzuki N et al. (2019)

© 2019, Suzuki et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license

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