Xenbase Image ID: 174980

Supplementary Figure 1. Expression of neural tissue-related genes in the brains of stage 61 wild type and TR-knockout tadpoles. Total cellular RNA was extracted from brains of NF stage 61 wild type, TR knockout, and TR beta knockout tadpoles, and qRT-PCR was conducted using gene-specific primers (Table S2 in Supporting Information). The relative mRNA expression level of the indicated gene to EF-1 mRNA is presented. Data are expressed as mean +/- SD. Biological replicate numbers of wild type, TR alpha-knockout, and TR Beta -knockout brain samples are five, five, and four, respectively. Image published in: Yaoita Y and Nakajima K (2018) Copyright © 2018. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue mbp xmbp X. tropicalis Throughout NF stage 61 brain atp1a2 fhm2, mhp2 X. tropicalis Throughout NF stage 61 brain atp1b3 atpb-3, beta-3, β3 ATPase subunit X. tropicalis Throughout NF stage 61 brain nefl NF-L, XNF-L X. tropicalis Throughout NF stage 61 brain nefm nef-m, nef3, nefm-a, nefm-b, nf-m X. tropicalis Throughout NF stage 61 brain syt2 X. tropicalis Throughout NF stage 61 brain Image source: Published Experiment + Assay Source Phenotypes and Disease Xtr Wt + TALEN thra + NF61 (RT-PCR) Fig S1. Expression Phenotype decreased amount atp1a2 expression in brain decreased amount atp1b3 expression in brain decreased amount mbp expression in brain decreased amount nefl expression in brain decreased amount nefm expression in brain decreased amount syt2 expression in brain Xtr Wt + TALEN thrb + NF61 (RT-PCR) Fig. S1. Expression Phenotype increased amount atp1a2 expression in brain increased amount atp1b3 expression in brain increased amount mbp expression in brain increased amount nefl expression in brain increased amount nefm expression in brain increased amount syt2 expression in brain Larger Image Printer Friendly View

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