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Figure S4. Representative Xenopus phenotypes caused by perturbation of the UDP-GlcNAc salvage pathway. (A) Representative images of posteriorized embryos due to DNagk mRNA injection and anteriorized embryos resulting from NagkT128M mRNA or 3-OMe-GlcNAc injection. (B) Representative images of posteriorized embryos due to injection of UDP-GlcNAc salvage pathway enzyme mRNAs. (C) Representative images of anteriorized embryos due to injection of MOs against the enzymes of the UDP-GlcNAc salvage pathway. (D) Representative images of embryos posteriorized by injection of sugars of the UDP-GlcNAc salvage pathway. (E) Representative images of embryos posteriorized or anteriorized by Dpagt1 mRNA or MO injections, respectively. (G) Representative image of an anteriorized embryo injected with Ngly1 mRNA. For injections, 1.5 ng mRNA, 1 pg MO, or 125 pmol compounds were used.

Image published in: Neitzel LR et al. (2019)

Copyright © 2019. Image reproduced with permission of the Publisher, Elsevier B. V.

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