Xenbase Image ID: 175366

Figure S6. Rescue of overexpression phenotypes of individual salvage pathway enzymes in Xenopus embryos by inhibiting downstream components of the UDP-GlcNAc pathway. (A) Co-injecting Nagk MO, Pgm3 MO, Uap1 MO, or Dpagt1 MO rescues the posteriorization phenotype of Nagk mRNA injections. (B) Co-injecting Nagk MO, Pgm3 MO, Uap1 MO, or Dpagt1 MO rescues the posteriorization phenotype of Pgm3 mRNA injections. (C) Co-injecting Nagk MO, Pgm3 MO, Uap1 MO, or Dpagt1 MO rescues the posteriorization phenotype of Uap1 mRNA injections. (D) Co-injecting Nagk MO, Pgm3 MO, Uap1 MO, or Dpagt1 MO rescues the posteriorization phenotype of Dpagt1 mRNA injections. Absolute numbers are indicated above bars. Results are aggregates of n≥3 replicates. Each dorsal blastomere was injected with 1.5 ng mRNA and/or 1 pg MO. Significance was calculated using Fisher’s exact test with Bonferroni correction. *ρ< 0.0127, **ρ< 0.00251, ***ρ< 0.000251. Image published in: Neitzel LR et al. (2019) Copyright © 2019. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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