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XB-IMG-175411

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Figure 5. Notch targets are unchanged during the cardiac oxidative stress response. Expression of (a) Hey1 and (b) Hes1, basic helix‐loop‐helix (bHLH) proteins downstream of Notch signaling, does not change significantly in KillerRed‐expressing and light‐treated tadpole hearts relative to uninjected controls over the first week after light activation (p > 0.05, Kruskal–Wallis test). Gene expression was measured relative to uninjected control hearts, using Eef1a as an endogenous control. Points indicate mean fold change at each time point, and vertical bars indicate range. n = 10 tadpoles per replicate, N = 2 replicates

Image published in: Jewhurst K and McLaughlin KA (2019)

Copyright © 2019. Image reproduced with permission of the Publisher, John Wiley & Sons.

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