Xenbase Image ID: 175555

Fig. 1. Desmosomes and desmoplakin in the epidermis of X. laevis embryos. A) Schematic showing a transverse section of the X. laevis embryonic epidermis based on actual histological sections. B) TEM images where black arrows indicate desmosomes located between outer epidermal cells. Scale bar = 1.8 μm. Inset shows higher magnification of a desmosome. Scale bar = 135 nm. C-D‴) Immunofluorescence of Dsp and beta-catenin in the epidermis. Dapi labeling of the nuclei was used as a counter stain. C-C‴) st. 19–20, in H arrows indicate regions where there is a less Dsp labeling and arrowheads indicate where there is enrichment of Dsp labeling. The same cells are indicated in panel C′. Scale bar = 27 μm. D-D‴) High magnification of a cell that appears to be apically emerging with high levels of Dsp and lower beta-catenin. Scale bar = 6 μm. D-D‴) High magnification of a cell that appears to be beginning to intercalate and has low levels of Dsp. Scale bar = 6 μm. Abbreviations = MCC = multiciliated cell, SVs = secretory vesicles, mito = mitochondria, TJ = tight junction, oe = outer epidermis, ie = inner epidermis. Image published in: Bharathan NK and Dickinson AJG (2019) Copyright © 2019. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue dsp.L X. laevis Sometime during NF stage 19 to NF stage 20 epidermis ctnnb1.L B-catenin, beta catenin, beta-catenin, ctnnb1-a, ctnnb1-b, β-catenin X. laevis Sometime during NF stage 19 to NF stage 20 epidermis Image source: Published Larger Image Printer Friendly View

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