Xenbase Image ID: 175567

Supplemental Figure 5: Decreased Dsp specifically in the trunk caused a reduction in tubulin positive cells. A) Schematic showing the blastomere injected with MO to target the trunk epidermis. B) Trunk epidermis of a representative embryo with CMO, labeled with tubulin (pink) and showing fluorescent tagged morpholino (green). C) Trunk epidermis of a representative embryo with DspMO1, labeled with tubulin (pink) and showing region lacking fluorescent tagged morpholino (green). Scale bar= D) Trunk epidermis of a representative embryo with DspMO1, labeled with tubulin (pink) and showing fluorescent tagged morpholino (green). Image published in: Bharathan NK and Dickinson AJG (2019) Copyright © 2019. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue tuba4b.L alpha tubulin, alpha-tubulin, tuba4, tuba4a X. laevis Throughout NF stage 32 multiciliated epidermal cell cilium Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + dsp MO + NF26-32 (immunohistochemistry) Fig. S 5 D Anatomical Phenotype abnormal development of multiciliated cell abnormally decreased number of multiciliated epidermal cell Disease skin disease Larger Image Printer Friendly View

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