Xenbase Image ID: 175670

Figure 5 Ex vivo Xenopus lens regeneration assay results following capsaicin or Spantide II treatment. A: Summary timeline of treatments in conjunction with the lentectomy procedure to remove the lens. Capsaicin treatment (Exp 1) is represented in orange and Spantide II treatment (Exp 2) is represented in blue. Time (days) is represented along the horizontal axis. B: Transverse section of control, untreated eye showing merged images of regenerated lens body stained with anti‐lens antibody (red fluorescence) and nuclei stained with DAPI (blue fluorescence). C: Graphical representation of the results of the ex vivo lens regeneration experiments in controls vs capsaicin‐treated cultures. D: Transverse section of larva treated with capsaicin, showing merged image of regenerated lens body. E: Graphical representation of ex vivo lens regeneration experiments in controls vs Spantide II–treated cultures. F: Transverse section of ex vivo cultured eye in Spantide II containing media, showing a regenerated lens body. Abbreviations: ln, lens; rt, retina. Scale bar in B,D,F = 140 μm Image published in: Perry KJ et al. (2019) Copyright © 2019. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

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