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Fig. 2. Xenopus pronephric and human metanephric nephrons share conserved tubule segmentation patterns based on gene expression data. The schematic represents nephron segments, designated by different colors, in the mammalian metanephric nephron (top) and the Xenopus pronephric nephron (bottom). The glomus/glomerulus filters blood across capillary walls into the proximal tubule, which filters various wastes out of the body through the remaining distal and connecting tubules. There are noted differences between the glomus and glomerulus in that the glomus deposits blood filtrate into the coelomic cavity. Additionally, Xenopus does not have a loop of Henle (grayed out in human schematic) or a true collecting duct (grayed out in human schematic), but instead has a region analogous to the connecting tubule closest to the distal tubule of the mammalian metanephric nephron (Raciti et al., 2008).

Image published in: Blackburn ATM and Miller RK (2019)

© 2019. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license

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