Xenbase Image ID: 175780

Fig. 3. Expression patterns are conserved between the human S-shaped body and the early Xenopus pronephros during development. Four different expression patterns (shown in different colors) of fundamental kidney proteins/mRNA were chosen to demonstrate the similarities between the developing human and Xenopus nephron. Schematics indicate where immunostaining of S-shaped body nephrons of week-16 to -17 human fetal kidneys is present (top) (Lindström et al., 2018), as well as in situ expression patterns of stage-33 Xenopus nephrons (bottom) (Xenbase.org). Schematics are positioned so that the proximal and distal regions of the human and Xenopus nephron expression patterns can be easily compared. The Xenopus kidney stage was chosen to match the approximate developmental time point of human S-shaped body nephrons, as both are representative of recently epithelialized nephrons. Note that pax2 is slightly more enriched at the nephrostomes in Xenopus (dark green). Image published in: Blackburn ATM and Miller RK (2019) © 2019. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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