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XB-IMG-1758

Xenbase Image ID: 1758


Fig. 9. Placodal gene expression patterns in early tail bud Xenopus embryos (stages 21–22) in lateral views (anterior is to the left) and right frontal views (inserts). Color-coded arrows and arrowheads are used for the identification of comparable regions of gene expression. Expression in the prospective lens placode (which is not yet thickened at this stage) is indicated by L. Colors are explained in the schematic drawing, which shows the distribution of placodes in a stage 21 embryo (modified after Schlosser and Northcutt, 2000; see Fig. 14 for detailed explanation). The unpaired adenohypophysial placode is located medial to the ventral part of the olfactory placode and is, thus, hidden behind the olfactory placode in this lateral perspective (indicated by light green arrow and Ad in brackets). Various shades of green identify placodes (including the prospective lens placode) expressing Pax6, yellow identifies the profundal placode expressing Pax3, and brown and pink jointly identify the posterior placodal area expressing Pax2 and Pax8, with pink being reserved for the subregion, which will form the otic vesicle. Blue–green asterisks indicate downregulation of the respective genes in the region of the prospective lens placode, whereas brown asterisks indicate downregulation of the respective genes in a region intervening between the anterior and posterior subregions of the posterior placodal area. The pink and brown asterisks in I indicate downregulation of FoxI1c expression in the dorsal part of the posterior placodal area. For detailed description, see text. For additional abbreviations, see Fig. 1.

Image published in: Schlosser G and Ahrens K (2004)

Copyright © 2004. Image reproduced with permission of the Publisher, Elsevier B. V.

GeneSynonymsSpeciesStage(s)Tissue
pax8.Lpax-8, XPax-8, XPax8X. laevisSometime during NF stage 21 to NF stage 22otic placode
pronephric mesenchyme
posterior placodal area
pax6.Lan2, mgda, pax-6, pax6-a, pax6-b, wagr, XLPAX6, xpax6X. laevisSometime during NF stage 21 to NF stage 22otic vesicle
lens placode
diencephalon
spinal cord
pax3.Scdhs, hup2, pax-3, pax3-a, pax3-b, Waardenburg syndrome 1, ws1, xpax3X. laevisSometime during NF stage 21 to NF stage 22hatching gland
brain
forebrain
midbrain
hindbrain
posterior placodal area
sox3.SSry, Xlsox3, xSox3, Xtsox3X. laevisSometime during NF stage 21 to NF stage 22otic vesicle
olfactory placode
optic vesicle
profundus ganglion
trigeminal ganglion
forebrain
midbrain
hindbrain
sox2.Lanop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2X. laevisSometime during NF stage 21 to NF stage 22otic vesicle
lens
lens placode
olfactory placode
trigeminal ganglion
forebrain
midbrain
hindbrain
msx1.Lhox-7, hox7, msx-1, msx1-a, msx1-b, Xhox-7.1, Xmsx-1, xmsx1X. laevisSometime during NF stage 21 to NF stage 22branchial arch
otic placode
hindbrain
spinal cord
ventral
tbx2.LET, tbx2-a, tbx2-b, Xltbx2, xtbx2X. laevisSometime during NF stage 21 to NF stage 22otic vesicle
trigeminal placode
lens placode
cement gland primordium
profundal placode
posterior placodal area
dlx3.Sai4, dlx3-a, dlx3-b, tdo, Xdll-2, xdlx3X. laevisSometime during NF stage 21 to NF stage 22trigeminal placode
cement gland primordium
olfactory placode
otic placode
eya1.Leyes absent-1, XEya1X. laevisSometime during NF stage 21 to NF stage 22trigeminal placode
olfactory placode
otic placode
six4.SD-Six4X. laevisSometime during NF stage 21 to NF stage 22trigeminal placode
olfactory placode
otic placode
profundal placode
posterior placodal area
six1.LXSix1X. laevisSometime during NF stage 21 to NF stage 22trigeminal placode
olfactory placode
otic placode
foxi4.LfoxI1c, foxi4.1, xfd-10X. laevisSometime during NF stage 21 to NF stage 22profundal placode
posterior placodal area
trigeminal placode
epibranchial placode
irx1.Liro, irx1-a, irx1-b, Xiro, Xiro1X. laevisSometime during NF stage 21 to NF stage 22trigeminal placode
otic placode
midbrain
pax2.LLOC108697493, pax-2, pax2-a, pax2-b, XPax-2, XPax2X. laevisSometime during NF stage 21 to NF stage 22optic vesicle
posterior placodal area
midbrain-hindbrain boundary
otic placode

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