Xenbase Image ID: 176380

Figure 6. Wnt signaling is required for the differentiation of CNC into head cartilage structures. Snai2:eGFP or Wnt reporter embryos were treated with XAV939 (B,B’, F,F’, 20 μM; J,J’, 5 μM), IWR1-endo (C,C’, G,G’, 40 μM; K,K’, 10 μM) or DMSO (vehicle control) from stage ~28 to ~35. Embryos were washed and cultured again to the indicated stages, and images were taken with a Zeiss Axiozoom.V16 epifluorescence microscope. A representative embryo from each treatment group is shown on the left, with upper and lower panels displaying ventral and dorsal views (with anterior at the top), respectively, of the same embryos, and statistics is shown in the graphs on the right. ***P < 0.001. Image published in: Li J et al. (2019) © The Author(s) 2019. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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