Xenbase Image ID: 176454

Fig. S1 Rpsa depletion does not affect development of other early developmental processes examined. A) Gross morphology of stage 45 control and rpsa depleted embryos. B) Optical coherence tomography of the craniofacial cartilages of stage 45 tadpoles injected with rpsa MO in one cell at the two cell stage, allowing comparison with the uninjected control side of the embryo. No significant differences were detected. C) Expression of nkx2.1, pax2 and hex is unaffected by depletion of rpsa. D) The laterality gene pitx2c is normally expressed in the left lateral mesoderm of rpsa morphants at stage 28 (green arrowheads). Image published in: Griffin JN et al. (2018) Copyright © 2018. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue pitx2 pitx2-A, pitx2-a, pitx2-b, pitx2c, xpitx2, xPtx2 X. tropicalis Throughout NF stage 28 lateral plate mesoderm heart trigeminal ganglion cement gland nkx2-1 nkx2.1, titf1, ttf1, Xnkx-2.1, xnkx2-1 X. tropicalis Throughout NF stage 37 and 38 lung bud forebrain hhex hex, tHex, XHex X. tropicalis Throughout NF stage 37 and 38 endoderm foregut liver alimentary system pax2 LOC108697493, pax-2, pax2-a, pax2-b, XPax-2, XPax2 X. tropicalis Throughout NF stage 37 and 38 otic vesicle pronephric nephrostome hindbrain spinal cord Image source: Published Larger Image Printer Friendly View

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