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Fig 5. Association of cardiac protein abundance and model system for selected proteins with known roles in human cardiac disease. A diagram of detected proteins with links to human heart disease reported in the KEGG database was created in Cytoscape showing relative protein abundance data across the 4 species examined here, as well as known protein–protein interactions between these heart disease–related proteins. See S8 Table for numerical data underlying figure. AFib, atrial fibrillation; ARVC, arrhythmogenic right ventricular cardiomyopathy; AVSD, atrioventricular septal defect; BAV, bicuspid aortic valve; BRS, brugada syndrome; CPVT, catecholaminergic polymorphic ventricular tachycardia; DCM, dilated cardiomyopathy; HCM, hypertrophic cardiomyopathy; LQTS, long QT syndrome; LVNC, left ventricular noncompaction; MVP, mitral valve prolapse; SVAS, congenital supravalvar aortic stenosis. Image published in: Federspiel JD et al. (2019) © 2019 Federspiel et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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