XB-IMG-23420
Xenbase Image ID: 23420
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Figure 3. Bmp antagonists disrupt early endoderm formation. One-cell embryos were injected vegetally with mRNA encoding the following Bmp Antagonists. B: DN-Alk3 (0.5 ng). C: Chordin (0.5 ng). D: Noggin (0.5 ng). The embryos were assayed by in situ hybridization with a probe for Sox17 beta at stage 10.5. A: A control injected with water. F-J: Two-cell-stage embryos were injected vegetally with 200 pg of lacZ mRNA, and mRNA for Chordin or Noggin as indicated. Embryos were fixed at stage 11, stained for lacZ using red gal substrate, and analyzed for Sox17 beta expression. Image published in: Wills A et al. (2008) Copyright © 2008. Image reproduced with permission of the Publisher, John Wiley & Sons.
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