Xenbase Image ID: 23729

Fig. 1. (A) Comparison of the predicted amino acid sequence of Xmxi1 with the mouse Mxi1 isoforms. GenBank accession number Xmxi1: DQ137875. (B) RT-PCR analysis of Xmxi1 at different stages of development. Histone H4 was used as a loading control. (C) Whole-mount in situ hybridization expression analysis of Xmxi1 in comparison with X-ngnr-1. (D–F) Double labeling of Xmxi1 and Sox3 expression. Sox3, red; Xmxi1, dark blue. (D) Stage 14, anterior view. (E) Stage 14, dorsal view. White arrowhead marks the lateral stripe of Xmxi1. (F) Transversal section of E. (G–N) Spatial expression of Xmxi1 during later stages of Xenopus development. (G) Stage 13, dorsal, anterior up. (H) Stage 16, dorsal view, anterior left. (I) S1 transversal section. (J) Stage 22, lateral. (K) Stage 27, anterior (L) Stage 37, lateral. (M) S2 transversal section. (N) S3 transversal section, dark brown staining at the roof of the spinal chord is pigmentation not Xmxi1 staining. el, epithelial layer; hb, hindbrain; i, intermediate; iz, intermediate zone; l, lateral; le, lens; m, medial; mb, midbrain; n, notochord; op, olfactory placode, r, retina; sl, sensory layer; st, stage; tg, trigeminal placodes; vz, ventricular zone. Image published in: Klisch TJ et al. (2006) Copyright © 2006. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue sox3.S Sry, Xlsox3, xSox3, Xtsox3 X. laevis Throughout NF stage 14 neural plate pre-chordal neural plate anterior neural fold chordal neural plate mxi1.L mxi, xmxi1 X. laevis Throughout NF stage 10.5 dorsal ectoderm mxi1.L mxi, xmxi1 X. laevis Throughout NF stage 11.5 chordal neural plate mxi1.L mxi, xmxi1 X. laevis Throughout NF stage 12.5 chordal neural plate mxi1.L mxi, xmxi1 X. laevis Throughout NF stage 14 chordal neural plate trigeminal placode mxi1.L mxi, xmxi1 X. laevis Throughout NF stage 16 chordal neural plate neuroectoderm sensorial layer of neurectoderm mxi1.L mxi, xmxi1 X. laevis Throughout NF stage 13 chordal neural plate trigeminal placode mxi1.L mxi, xmxi1 X. laevis Throughout NF stage 22 olfactory placode neural tube hindbrain optic vesicle mxi1.L mxi, xmxi1 X. laevis Throughout NF stage 27 olfactory placode optic vesicle midbrain hindbrain mxi1.L mxi, xmxi1 X. laevis Throughout NF stage 37 and 38 optic vesicle retina hindbrain midbrain ventricular zone neurog2.L atoh4, neurog2-a, neurog2-b, neurogenin 2, neurogenin-2, neurogenin-related-1, neurogenin2, ngn-2, ngn2, ngnr, ngnr 1a, Ngnr-1, Ngnr1, X-ngnr-1, xngn2, Xngnr-1, XNgnr1 X. laevis Throughout NF stage 11.5 chordal neural plate neuron lateral neurog2.L atoh4, neurog2-a, neurog2-b, neurogenin 2, neurogenin-2, neurogenin-related-1, neurogenin2, ngn-2, ngn2, ngnr, ngnr 1a, Ngnr-1, Ngnr1, X-ngnr-1, xngn2, Xngnr-1, XNgnr1 X. laevis Throughout NF stage 12.5 chordal neural plate neuron trigeminal placode neurog2.L atoh4, neurog2-a, neurog2-b, neurogenin 2, neurogenin-2, neurogenin-related-1, neurogenin2, ngn-2, ngn2, ngnr, ngnr 1a, Ngnr-1, Ngnr1, X-ngnr-1, xngn2, Xngnr-1, XNgnr1 X. laevis Throughout NF stage 14 chordal neural plate trigeminal placode Image source: Published Larger Image Printer Friendly View

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