Xenbase Image ID: 23744

Fig. 7. SRp38 is induced by neuroD. (A) Dorsal views of SRp38 expression are pictured at stage 21. Left: control. Right: injection of 250 pg of neuroD into one cell at two cell-stage induces robust expression of SRp38. (B) RT-PCR on ectodermal explants. Injection of 250 pg of neuroD (+N) induces expression of SRp38. EF1α is a loading control and muscle actin (MA) controls for mesodermal contamination. (C) SRp38 northern blot on total RNA in embryos overexpressing increasing doses of neuroD (125 pg to 500 pg) results in increasing amounts of SRp38 RNA. (D) SRp38 is itself regulated by neuroD, suggesting it is a component of a neuroD-induced mechanism serving to limit neurogenesis. Image published in: Liu KJ and Harland RM (2005) Copyright © 2005. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue srsf10 fusip1, fusip2, nssr, sfrs13, srp38, srrp40, tasr, tasr1, tasr2 Xenopus Throughout NF stage 21 neural plate trigeminal ganglion pre-chordal neural plate anterior neural fold neuroectoderm Image source: Published Larger Image Printer Friendly View

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