Xenbase Image ID: 24086

Figure 2. Differentiation of anteroventral cells is regulated by BMP and Notch. Anterior (A-D,I,J,L,N,O), lateral (E-H), or dorsal (K,M,P) views of neurula to early tail bud embryos are shown. A,B: Stage 13 embryo stained with BMP4 alone (A) or double stained with Phox2a (arrowhead) and BMP4 (B). C,D: Embryos injected with tBR mRNA show a reduction of Phox2a and tyrosine hydroxylase (TH) expression in the anteroventral region. E-H: Induction of Phox2a and TH by Xash1 is reduced by coinjection of tBr. I: Delta1 is transiently expressed in the anteroventral cells (arrowhead). J,K: Embryos injected with Notch1 ICD or Su(H)Ank show a decrease of IA1 expression in the neural plate primary neurons and anteroventral cells (arrowheads). L,M: Embryos injected with Delta1stu or Su(H)DBM mRNA show an increase of IA1 expression in the neural plate primary neurons, trigeminal placodes, and anteroventral cells (arrowheads). Image published in: Parlier D et al. (2008) Copyright © 2008. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue bmp4.L bmp2b, bmp2b1, bmp-4, bmp4-a, bmp4-b, DVR-4, ofc11, XBMP-4, xbmp4, zyme X. laevis Throughout NF stage 13 cement gland primordium anterior neural fold dll1.L delta-1, Delta-1, delta1, x-delta, X-delta-1, Xdelta-1, Xdelta1, XDelta1 X. laevis Throughout NF stage 20 nervous system neural plate anterior anterior neural fold neuroectoderm sensorial layer of neurectoderm phox2a.S LOC108710089, phox2, xphox2a X. laevis Throughout NF stage 20 head anterior ventral insm1.L IA1 X. laevis Throughout NF stage 20 neuron head nervous system neural plate anterior neural fold anterior th.S dyt14, dyt5b, tyh, tyrosine 3-monooxygenase, tyrosine hydroxylase X. laevis Throughout NF stage 20 neuron head nervous system neuroectoderm Image source: Published Larger Image Printer Friendly View

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