Xenbase Image ID: 24552

Fig. 2. Expression pattern of Snail and Slug analysed by whole-mount in situ hybridisation. (A) Dorsal view of a stage 9 embryo. An, animal pole; Veg, vegetal pole. Notice the expression in the dorsal marginal zone. (B) Dorsal view of a stage 11.5 embryo. b, dorsal blastopore lip. Snail is expressed in the prospective neural crest (arrowheads) and in a continuous band at the anterior border of the neural plate (arrow). (C) Same embryo as in B (stage 11.5) but hybridised for Slug expression. No expression is seen in the ectoderm (white arrowheads). (D) Dorsovegetal view of the embryo shown in B. Arrow indicates Snail staining in the anterior ectoderm. This is also visible around the blastopore lip in the marginal zone, apart from the dorsal region where Snail has been switched off. (E) Dorsal view of a stage 12.5 embryo. Expression is visible in the mesoderm near the blastopore and in the prospective neural crest (arrowhead). An, animal pole; Veg, vegetal pole. (F) Earliest Slug expression. Dorsal view of a stage 12.5 embryo. Expression in the prospective neural crest (arrowheads). An, animal pole; Veg, vegetal pole. (G) Anterior view of a stage 17 embryo. Expression in the superficial (white arrowheads) and in the deep (black arrowheads) layers of the ectoderm and in the anterior neural fold (a, arrow). (H,I) Schematic representation of Snail and Slug expression at stages 11 and 12.5. Anterior is upwards and posterior is downwards. Image published in: Aybar MJ et al. (2003) Copyright © 2003. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue snai2.L slug, snai2-a, snai2-b, Snail2, xSlu, xslug, XSnail2 X. laevis Throughout NF stage 11.5 upper blastopore lip neural crest snai2.L slug, snai2-a, snai2-b, Snail2, xSlu, xslug, XSnail2 X. laevis Throughout NF stage 9 dorsal marginal zone snai2.L slug, snai2-a, snai2-b, Snail2, xSlu, xslug, XSnail2 X. laevis Throughout NF stage 12.5 neural crest mesoderm snai2.L slug, snai2-a, snai2-b, Snail2, xSlu, xslug, XSnail2 X. laevis Throughout NF stage 17 sensorial layer of neurectoderm superficial neuroectoderm anterior neural fold Image source: Published Larger Image Printer Friendly View

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