Xenbase Image ID: 24554

Fig. 4. The expansion of the neural crest territory induced by Snail or Slug does not require cell proliferation. One blastomere of a two-cell stage embryo was injected with 700 pg of Xsnail-GR mRNA (A,B) or Xslug-GR (C,D), treated with dexamethasone and HUA at stage 12.5, fixed at stage 19 and the expression of the neural crest markers Snail (A,C) and Slug (B,D) analysed. The injected side, which can be recognised by the blue FLDx staining, is indicated by the arrowhead. Note the expansion in the expression of the neural crest markers on the injected side. (E) HUA treated and (F) control embryos stained for histone H3 to verify the blockade in cell proliferation induced by the treatment. The inset shows a higher magnification of the embryos. Note the staining in absence of HUA treatment, but the lack of staining after HUA treatment. Image published in: Aybar MJ et al. (2003) Copyright © 2003. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue snai1.S LOC108702592, sna, snail, snail1, xSna, Xsnail X. laevis Throughout NF stage 19 neural crest neuroectoderm snai2.L slug, snai2-a, snai2-b, Snail2, xSlu, xslug, XSnail2 X. laevis Throughout NF stage 19 neural crest neuroectoderm Image source: Published Larger Image Printer Friendly View

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